Cell Type Knowledge Explorer

Cell Type Knowledge Explorer

The Cell Type Knowledge Explorer aggregates and summarizes multi-modal information about human, marmoset, and mouse cell types in the primary motor cortex. High-throughput, single-cell transcriptomic, and epigenomic profiling demonstrate broad conservation of molecular cell type identities across these three species. The Cell Type Knowledge Explorer is powered by a data-driven ontology, which drives search and connects these data to external knowledge about cell types. Each cell type has a unique Cell Type Knowledge Card, which provides summary text and visualizations of available data. These data were generated as part of the BRAIN Initiative Cell Census Network (BICCN) and described in detail in the BICCN flagship publication.  

The Cell Types Knowledge Explorer will enable the neuroscience community to: 

• Explore features of primary motor cortex cell types including gene expression, spatial location and electrophysiological properties 

• Identify primary motor cortex cell types that are conserved across mammalian species 

• Access underlying BICCN data sets and related data exploration tools such as epigenetics browsers and tools for cell type mapping