The Synaptic Physiology Dataset allows users to explore interactions between cell subclasses in mouse and human cortex. There are a variety of ways to access the data based on your interests.
Online Jupyter notebooksHosted by mybinder.org, these notebooks provide an interactive environment for accessing, analyzing, and visualizing results from the Synaptic Physiology Dataset. This provides a quick way to begin interacting with the data in your browser, but some Python experience is recommended. Note: mybinder.org instances will shut down after 10 minutes of inactivity. These are great for quickly exploring the dataset, but not appropriate for prolonged data analysis. |
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Interactive desktop toolsExplore the Synaptic Physiology Dataset with interactive tools. Choose cell classes of interest and synaptic metrics to see an overview of cortical synaptic physiology. Requires installation of a Python programming environment on your local machine. Getting started with Synaptic Physiology tools |
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Access the data directly via our APIThe Synaptic Physiology Python programming packages provide access to three sqlite databases, described below, as well as the original NWBv1 (HDF5) data files. Getting started with the Synaptic Physiology API |
The Synaptic Physiology Dataset is available as three different sqlite files, each increasing in content and size. It is recommended that you download the database files directly from our API or contact us for other options.
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Small(~170 MB) |
Medium(~7 GB) |
Full(>160 GB) |
experiment metadatatissue source, experimental conditions |
✓ | ✓ | ✓ |
chemical / electrical connectionsconnection probability |
✓ | ✓ | ✓ |
cell propertiestransgenic class, layer, morphology, intrinsic physiology |
✓ | ✓ | ✓ |
per-connection average propertiesstrength, kinetics, dynamics, averaged synaptic responses, electrical connection properties |
✓ | ✓ | ✓ |
per-connection synaptic release modelsquantal release parameters, short-term plasticity |
✓ | ✓ | ✓ |
per-stimulus response propertiescurve fits to individual synaptic responses |
✓ | ✓ | |
per-stimulus spike propertiestiming and measurements of individual presynaptic spikes |
✓ | ✓ | |
stimulus / recording metadata |
✓ | ✓ | |
per-stimulus response datatime-series data for every presynaptic spike and corresponding postsynaptic recording |
✓ |
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